Cardiomyopathy in cirrhosis: from pathophysiology to clinical care

Cirrhotic cardiomyopathy; Pathophysiology and clinical approach

Cardiac dysfunction is considerably discovered in patients with liver cirrhosis. Cirrhotic cardiomyopathy (CCM) has newly been assigned to as an entity separate of the cirrhosis etiology. Increased cardiac output due to hyperdynamic circulation, left ventricular dysfunction (systolic and diastolic) and certain electro-physiological abnormal findings are pathophysiological features of the diseas...

Alcoholic cardiomyopathy: incidence, clinical characteristics, and pathophysiology.

In the United States, in both sexes and all races, long-term heavy alcohol consumption (of any beverage type) is the leading cause of a nonischemic, dilated cardiomyopathy, herein referred to as alcoholic cardiomyopathy (ACM). ACM is a specific heart muscle disease of a known cause that occurs in two stages: an asymptomatic stage and a symptomatic stage. In general, alcoholic patients consuming...

Sepsis: From Pathophysiology to Individualized Patient Care

Sepsis has become a major health economic issue, with more patients dying in hospitals due to sepsis related complications compared to breast and colorectal cancer together. Despite extensive research in order to improve outcome in sepsis over the last few decades, results of large multicenter studies were by-and-large very disappointing. This fiasco can be explained by several factors, but one...

Bench-to-bedside review: Mobilizing patients in the intensive care unit – from pathophysiology to clinical trials

As the mortality from critical illness has improved in recent years, there has been increasing focus on patient outcomes after hospital discharge. Neuromuscular weakness acquired in the intensive care unit (ICU) is common, persistent, and often severe. Immobility due to prolonged bed rest in the ICU may play an important role in the development of ICU-acquired weakness. Studies in other patient...

Pathophysiology dilated cardiomyopathy pdf